Figures
- FIGURE 1.
Statistical analysis. Course of chronic obstructive pulmonary disease (COPD) in a) Toll-like receptor (TLR)5 and b) TLR4. a) □: C1174T homozygous; ░: C1174T heterozygous; ▓: wildtype homozygous. b) ░: Asp299Gly/Thr399Ile heterozygous; ▓: wildtype homozygous. *: p<0.05; #: p = 0.138; ¶: p = 0.414; +: p = 0.026; §: p = 0.124; ƒ: p = 0.226; ##: p = 0.136.
Tables
- Table 1—
TLR5: statistical analysis (TLR5392STOP)
Total n Wildtype +/+ TLR5-polymorphism heterozygous +/m TLR5-polymorphism homozygous m/m Allele frequency p-value COPD total 138 114 (82.61) 22 (15.94) 2 (1.45) 26/276 (9.42) 0.138 COPD stable course 54 41 (75.93) 12 (22.22) 1 (1.85) 14/108 (12.96) 0.026 COPD unstable course 84 73 (86.90) 10 (11.90) 1 (1.20) 12/168 (7.14) 0.414 Control 135 121 (89.63) 14 (10.37) 0 14/270 (5.19) Data are presented as n (%), unless otherwise stated. TLR: Toll-like receptor.
- Table 2—
TLR4: statistical analysis (Asp299Gly/Thr399lle)
Total n Wildtype +/+ TLR4-polymorphism heterozygous +/m TLR4-polymorphism homozygous m/m Allele frequency p-value COPD total 138 124 (89.86) 14 (10.14) 0 14/276 (5.07) 0.124 COPD stable course 54 47 (87.04) 7 (12.96) 0 7/108 (6.48) 0.136 COPD unstable course 84 77 (91.67) 7 (8.33) 0 7/168 (4.17) 0.226 Control 135 128 (94.87) 7 (5.13) 0 7/270 (2.59) Data are presented as n (%), unless otherwise stated. TLR: Toll-like receptor.
Vol 15 Issue 101
Table of Contents
A stop codon polymorphism of toll-like receptor 5 is associated with a stable course of chronic obstructive lung disease
