[HTML][HTML] Second-line combination therapies in nonsmall cell lung cancer without known driver mutations

MV Bluthgen, B Besse - European Respiratory Review, 2015 - Eur Respiratory Soc
In advanced nonsmall cell lung cancer (NSCLC) patients, platinum-based combination
chemotherapy is standard treatment in the first-line setting; however, the large majority of …

Second-line treatment of non-small cell lung cancer: new developments for tumours not harbouring targetable oncogenic driver mutations

PC Barnfield, PM Ellis - Drugs, 2016 - Springer
Platinum-based doublet chemotherapy with or without bevacizumab is the standard of care
for the initial management of advanced and metastatic non-small cell lung cancer (NSCLC) …

Treatment of advanced non-small cell lung cancer with driver mutations: current applications and future directions

J Zhong, H Bai, Z Wang, J Duan, W Zhuang… - Frontiers of …, 2023 - Springer
With the improved understanding of driver mutations in non-small cell lung cancer (NSCLC),
expanding the targeted therapeutic options improved the survival and safety. However …

[HTML][HTML] The continuing role of chemotherapy for advanced non-small cell lung cancer in the targeted therapy era

Z Lwin, JW Riess, D Gandara - Journal of thoracic disease, 2013 - ncbi.nlm.nih.gov
There have been remarkable advances in the targeted treatment of advanced non-small cell
lung cancer (NSCLC) over the past several years. Survival outcomes are steadily improving …

Cytotoxic chemotherapy in advanced non–small cell lung cancer with poor performance status: A retrospective analysis from routine clinical practice

H Kancharla, N Gundu, N Pathak… - Current Problems in …, 2020 - Elsevier
Background: Platinum-based combination chemotherapy is recommended as the standard
treatment for patients with advanced non–small-cell lung cancer (NSCLC), but its benefit is …

Chemotherapy for advanced-stage non–small cell lung cancer

L Du, D Morgensztern - The Cancer Journal, 2015 - journals.lww.com
Use of platinum-based chemotherapy doublets is the standard of care for patients with
advanced-stage non–small cell lung cancer, being associated with improved survival …

[HTML][HTML] Advanced non-small cell lung cancer: on relapse rechallenge the tumor, not the patient

ME Froudarakis, E Briasoulis - BMC Research Notes, 2010 - Springer
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality in the
world. The majority of NSCLC patients are diagnosed with advanced-stage disease and …

Chemotherapy of advanced non-small cell lung cancer

R Pirker, W Minar - Controversies in the Treatment of Lung Cancer, 2010 - karger.com
Patients with advanced NSCLC receive palliative chemotherapy with platinum-based
doublets. Cisplatin-based doublets are preferred in patients with good performance status …

[HTML][HTML] Advanced non-small-cell lung cancer: how to manage non-oncogene disease

A De Giglio, A Di Federico, C Deiana, B Ricciuti… - Drugs in …, 2022 - ncbi.nlm.nih.gov
The therapeutic approach to patients affected by advanced non-small-cell lung cancer
(NSCLC) is facing rapid and continuous evolution. In recent years, the emergence of new …

New avenues for second-line treatment of metastatic non-small-cell lung cancer

C Gridelli, P Maione, A Rossi, M Falanga… - Expert review of …, 2009 - Taylor & Francis
Platinum-based doublets are the standard first-line therapy for patients with advanced non-
small-cell lung cancer, with approximately a third of patients obtaining an objective response …