Exacerbations are a frequent event in the evolution of chronic obstructive pulmonary
disease (COPD) patients. Individuals with COPD have a mean of 1–3 episodes per year …

Exacerbations of chronic obstructive pulmonary disease (COPD) are natural events in the
progression of the disease, and are characterised by acute worsening of symptoms …

Exacerbations of chronic obstructive pulmonary disease (COPD) are defined as sustained
worsening of a patient's condition beyond normal day-to-day variations that is acute in onset …

Exacerbations have significant impact on the morbidity and mortality of patients with chronic
obstructive pulmonary disease. Most guidelines emphasise prevention of exacerbations by …

Severe exacerbations of COPD, ie, those leading to hospitalization, have profound clinical
implications for patients and significant economic consequences for society. The prevalence …

Introduction: Exacerbations of chronic obstructive pulmonary disease (COPD) are important
events in the natural history of the disease that have significant impact on important …

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide. While COPD is a mainly chronic disease, a substantial number of patients suffer …

Acute exacerbations of chronic obstructive pulmonary disease (COPD)—characterized by
shortness of breath, increased sputum production, increased purulence, or a combination of …

140 Editorial showed that these drugs reduce the annual exacerbation rate by 29%
compared with placebo [20]. Data from several large controlled studies have shown no …

Exacerbations of COPD represent an important medical and health care problem. Certain
susceptible patients suffer recurrent exacerbations and as a consequence have a poorer …