Biologics in severe difficult-to-treat asthma: find the right niche!

M Humbert - European Respiratory Review, 2009 - Eur Respiratory Soc
As stated by GAGA et al.[1] in this issue of the European Respiratory Review, severe asthma
still causes substantial mortality and morbidity and has a considerable economic impact …

Role of biologics in asthma

MC McGregor, JG Krings, P Nair… - American journal of …, 2019 - atsjournals.org
Patients with severe uncontrolled asthma have disproportionally high morbidity and
healthcare utilization as compared with their peers with well-controlled disease. Although …

Biologicals for severe asthma: what we can learn from real-life experiences?

D Bagnasco, M Caminati… - Current Opinion in …, 2020 - journals.lww.com
Biologicals for severe asthma: what we can learn from real-l... : Current Opinion in Allergy and
Clinical Immunology Biologicals for severe asthma: what we can learn from real-life experiences …

Emerging biologics in severe asthma

ID Pavord, B Hilvering… - … and Allergy Clinics, 2016 - immunology.theclinics.com
Asthma is a common chronic inflammatory disease of the airways that affects 300 million
people worldwide. 1 Many patients achieve satisfactory control of the clinical manifestations …

What is the current role of biologics in the management of patients with severe refractory asthma?

S Draikiwicz, J Oppenheimer - Annals of Allergy, Asthma & …, 2016 - annallergy.org
Approximately 300 million people worldwide have asthma, with the number of affected
individuals projected to continue to increase during the next decade. 1 Current asthma …

Real-life studies of biologics used in asthma patients: key differences and similarities to trials

E Heffler, G Paoletti, V Giorgis, F Puggioni… - Expert Review of …, 2019 - Taylor & Francis
Introduction: The precision medicine approach that is now mandatory for severe asthma
management includes the use of novel biologic agents blocking specific immunological …

Biologics for severe asthma—Which, when and why?

PA Shah, C Brightling - Respirology, 2023 - Wiley Online Library
Asthma is a common chronic inflammatory condition of the airways that affects about 350
million people globally. In 5%–10% of individuals, it is severe, with considerable morbidity …

Biologics in the treatment of severe asthma

S Quirce, E Phillips-Angles… - Allergologia et …, 2017 - Elsevier
Severe asthma is defined as asthma which requires treatment with high dose inhaled
corticosteroids and with a second controller drug to prevent it from becoming uncontrolled or …

Biological treatments for severe asthma: a major advance in asthma care

WW Busse - Allergology International, 2019 - jstage.jst.go.jp
abstract Asthma is a heterogeneous disease with considerable variability noted in disease
severity, patterns of airway inflammation, and achievement of disease control on current …

Biologic therapy and novel molecular targets of severe asthma

AN Pepper, H Renz, TB Casale, H Garn - The Journal of Allergy and …, 2017 - Elsevier
Treatment options for severe or uncontrolled asthma are increasing, especially pertaining to
novel biologic therapies. The 2 primary asthma endotypes, T2 high and T2 low, are defined …