Treatment of pulmonary exacerbations in cystic fibrosis

JM Bhatt - European Respiratory Review, 2013 - Eur Respiratory Soc
Pulmonary exacerbations have very important consequences in cystic fibrosis (CF), both in
terms of current morbidity as well as implications for long term morbidity and mortality. Even …

[HTML][HTML] Treatment of lung infection in patients with cystic fibrosis: current and future strategies

G Döring, P Flume, H Heijerman, JS Elborn… - Journal of Cystic …, 2012 - Elsevier
In patients with cystic fibrosis (CF) lung damage secondary to chronic infection is the main
cause of death. Treatment of lung disease to reduce the impact of infection, inflammation …

[HTML][HTML] Prolongation of antibiotic treatment for cystic fibrosis pulmonary exacerbations

V Waters, S Stanojevic, M Klingel, J Chiang… - Journal of Cystic …, 2015 - Elsevier
Background Pulmonary exacerbations frequently lead to an irrevocable loss of lung function
in cystic fibrosis (CF) patients. Although extended antibiotic duration has not been shown to …

Acute pulmonary exacerbations in cystic fibrosis

CH Goss - Seminars in respiratory and critical care medicine, 2019 - thieme-connect.com
With the improving survival of cystic fibrosis (CF) patients and the advent of highly effective
cystic fibrosis transmembrane conductance regulator therapy, the clinical spectrum of this …

Pulmonary exacerbation: towards a definition for use in clinical trials. Report from the EuroCareCF Working Group on outcome parameters in clinical trials

D Bilton, G Canny, S Conway, S Dumcius, L Hjelte… - Journal of Cystic …, 2011 - Elsevier
Pulmonary exacerbations represent a key outcome variable in clinical trials of cystic fibrosis
(CF). As there is variation in the trigger for use of intravenous antibiotics compared to the use …

Exacerbations in cystic fibrosis· 1: epidemiology and pathogenesis

CH Goss, JL Burns - Thorax, 2007 - thorax.bmj.com
With the improving survival of patients with cystic fibrosis (CF), the clinical spectrum of this
complex multisystem disease continues to evolve. One of the most important clinical events …

Pulmonary exacerbations in cystic fibrosis

AE Stenbit, PA Flume - Current opinion in pulmonary medicine, 2011 - journals.lww.com
We have established recommendations on specific treatment of a pulmonary exacerbation
and have outlined the areas where we need better information on appropriate therapies …

Location and duration of treatment of cystic fibrosis respiratory exacerbations do not affect outcomes

JM Collaco, DM Green, GR Cutting… - American journal of …, 2010 - atsjournals.org
Rationale: Individuals with cystic fibrosis (CF) are subject to recurrent respiratory infections
(exacerbations) that often require intravenous antibiotic treatment and may result in …

Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis

MN Hurley, AP Prayle, P Flume - Cochrane Database of …, 2015 - cochranelibrary.com
Background Cystic fibrosis is a multi‐system disease characterised by the production of thick
secretions causing recurrent pulmonary infection, often with unusual bacteria. Intravenous …

Short-term and long-term response to pulmonary exacerbation treatment in cystic fibrosis

SL Heltshe, CH Goss, V Thompson, SD Sagel… - Thorax, 2016 - thorax.bmj.com
Background Treatment of pulmonary exacerbations (PEx) in cystic fibrosis (CF) varies widely
with no consensus on management practices or best indicators of therapeutic success. To …