Structure of influenza virus haemagglutinin complexed with a neutralizing antibody

T Bizebard, BÃ Gigant, P Rigolet, B Rasmussen, O Diat… - Nature, 1995 - nature.com
HAEMAGGLUTININ (HA) is the influenza surface glycoprotein that interacts with infectivity-neutralizing
antibodies. As a consequence of this immune pressure, it is the variable virus …

[HTML][HTML] Functions of DEAD-box proteins in bacteria: current knowledge and pending questions

I Iost, T Bizebard, M Dreyfus - Biochimica et Biophysica Acta (BBA)-Gene …, 2013 - Elsevier
DEAD-box proteins are RNA-dependent ATPases that are widespread in all three kingdoms
of life. They are thought to rearrange the structures of RNA or ribonucleoprotein complexes …

An antibody that prevents the hemagglutinin low pH fusogenic transition

C Barbey-Martin, B Gigant, T Bizebard, LJ Calder… - Virology, 2002 - Elsevier
We have determined the structure of a complex of influenza hemagglutinin (HA) with an
antibody that binds simultaneously to the membrane-distal domains of two HA monomers, …

The mechanism of neutralization of influenza virus infectivity by antibodies

M Knossow, T Bizebard, B Gigant… - Foundations of …, 2002 - journals.iucr.org
The Haemagglutinin (HA) is the influenza surface glycoprotein that interacts with infectivity
neutralizing antibodies. As a consequence of this immune pressure, it is the variable virus …

A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site

D Fleury, B Barrère, T Bizebard, RS Daniels… - Nature structural …, 1999 - nature.com
… Thierry Bizebard … . In addition, we produced and purified HC19 and HC45 antibodies
and Fab fragments as described by Bizebard et al. . … Thierry Bizebard

Antigen distortion allows influenza virus to escape neutralization

…, JJ Skehel, M Knossow, T Bizebard - Nature structural …, 1998 - nature.com
The structure of the hemagglutinin (HA) of a mutant influenza virus that escapes neutralization
by a monoclonal antibody shows that the mutation causes changes in HA structure which …

Studies on Three E. coli DEAD-Box Helicases Point to an Unwinding Mechanism Different from that of Model DNA Helicases

T Bizebard, I Ferlenghi, I Iost, M Dreyfus - Biochemistry, 2004 - ACS Publications
… P-labeled-RNA present in duplex form after time t was taken as R t (double-stranded)/(R t
(single-stranded) + R t (double-stranded)), where R t (x) represents the amount of radioactivity (…

Membrane fusion by influenza hemagglutinin

JJ Skehel, T Bizebard, PA Bullough… - Cold Spring Harbor …, 1995 - symposium.cshlp.org
Enveloped viruses infect cells by binding to cellsurface receptors and then fusing their
membranes with cellular membranes to deliver their genetic material into the ceil. Fusion can …

Structural evidence for recognition of a single epitope by two distinct antibodies

…, JJ Skehel, M Knossow, T Bizebard - Proteins: Structure …, 2000 - Wiley Online Library
… et al.42 have shown that two different T cell receptors can recognize the same MHC/peptide …
by redundancy are profitable both to the B-cell and to the T-cell arms of the immune system. …

Cold adaptation in DEAD-box proteins

…, F Lorieux, F Allemand, M Dreyfus, T Bizebard - Biochemistry, 2010 - ACS Publications
Spontaneous rearrangements of RNA structures are usually characterized by large activation
energies and thus become very slow at low temperatures, yet RNA structure must remain …