Pulmonary hypertension in chronic lung disease and hypoxia

…, JA Barbera, SP Gaine, S Harari… - European …, 2019 - Eur Respiratory Soc
… However, in COPD patients with moderate resting oxygen desaturation (S pO 2 89–93%)
or exercise-induced oxygen desaturation (S pO 2 <90% for ≥10 s), LTOT does not provide …

Updated clinical classification of pulmonary hypertension

…, M Delcroix, CP Denton, CG Elliott, SP Gaine… - Journal of the American …, 2009 - jacc.org
… (TRV) ≥2.5 m/s, found that 32% of patients had PH (57). However, using a TRV >2.5 m/s on
… When a TRV >3.0 m/s was used, corresponding to an estimated systolic PAP of >41 mm Hg, …

Diagnosis and differential assessment of pulmonary arterial hypertension

…, O Sitbon, MJ Krowka, H Olschewski, S Gaine - Journal of the American …, 2004 - jacc.org
… m/s at baseline to a peak of 2.46 m/s at mid-level exercise and to 2.27 m/s at peak exercise
(240 W); in trained athletes the baseline value is 2.25 m/s and increases to 3.41 m/s at peak …

Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European …

…, JA Barbera, M Beghetti, P Corris, S Gaine… - European heart …, 2009 - academic.oup.com
… Sean Gaine … a Or large accuracy or outcome trial(s) in the case of diagnostic tests or
strategies. … a Or large accuracy or outcome trial(s) in the case of diagnostic tests or strategies. …

Changing demographics, epidemiology, and survival of incident pulmonary arterial hypertension: results from the pulmonary hypertension registry of the United …

…, PA Corris, AJ Fisher, JL Lordan, S Gaine… - American journal of …, 2012 - atsjournals.org
Rationale: Incident pulmonary arterial hypertension was underrepresented in most pulmonary
hypertension registries and may have a different disease profile to prevalent disease. …

Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease: a randomized, controlled trial

…, S Shapiro, TA Medsger Jr, SP Gaine… - Annals of internal …, 2000 - acpjournals.org
Background: Pulmonary hypertension is a progressive and often fatal complication of the
scleroderma spectrum of disease for which no treatment has been proven effective in a …

Long-term outcome of patients with chronic thromboembolic pulmonary hypertension: results from an international prospective registry

…, JA Barberà, M de Perrot, MM Hoeper, S Gaine… - Circulation, 2016 - Am Heart Assoc
… Dr Pepke-Zaba has received honoraria for lecturing from Bayer, Actelion, and GSK, is on
advisory boards for Actelion, Bayer, consultant’s fees from Actelion and educational and …

Dynamic risk stratification of patient long-term outcome after pulmonary endarterectomy: results from the United Kingdom National Cohort

…, K Dimopoulos, SJ Wort, S Gaine, S Moledina… - Circulation, 2016 - Am Heart Assoc
… 590 dynes·s −1 ·cm −5 was correlated with poor longer-term outcome. Our results show a
slightly lower threshold with 416 dynes·s −1 ·cm −5 for all-cause mortality and 425 dynes·s −1 ·…

Elderly patients diagnosed with idiopathic pulmonary arterial hypertension: results from the COMPERA registry

…, HJ Seyfarth, KM Olsson, CF Opitz, SP Gaine… - International journal of …, 2013 - Elsevier
… The author(s) of this manuscript have certified that they … mm Hg, PVR 963 ± 501 dyn.s.cm −
5 ) was similar to previous … ± 10 mm Hg, PVR 667 ± 363 dyn.s.cm − 5 ), and our data suggest …

Primary pulmonary hypertension

SP Gaine, LJ Rubin - The Lancet, 1998 - thelancet.com
Primary pulmonary hypertension (PPH) is a progressive disease characterised by raised
pulmonary vascular resistance, which results in diminished right-heart function due to …