[HTML][HTML] Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice

RHE Cloots, S Sankaranarayanan, ME Poynter… - BMC pulmonary …, 2017 - Springer
Background (Over-)expression of arginase may limit local availability of arginine for nitric
oxide synthesis. We investigated the significance of arginase1 (ARG1) for the development of …

[HTML][HTML] Hypoargininemia exacerbates airway hyperresponsiveness in a mouse model of asthma

RHE Cloots, ME Poynter, E Terwindt, WH Lamers… - Respiratory …, 2018 - Springer
Background Asthma is a chronic respiratory condition, with airway hyperresponsiveness (AHR)
and inflammation as hallmarks. The hypothesis that the substantially increased …

Multi-scale mechanics of traumatic brain injury: predicting axonal strains from head loads

RJH Cloots, JAW Van Dommelen, S Kleiven… - … and modeling in …, 2013 - Springer
… RJH Cloots et al. … RJH Cloots et al. … In addition to the multi-scale method, an anisotropic
equivalent strain measure (Cloots et al. 2012) was implemented in the FE head model to …

[HTML][HTML] Biomechanics of traumatic brain injury: influences of the morphologic heterogeneities of the cerebral cortex

RJH Cloots, HMT Gervaise… - Annals of biomedical …, 2008 - Springer
Traumatic brain injury (TBI) can be caused by accidents and often leads to permanent health
issues or even death. Brain injury criteria are used for assessing the probability of TBI, if a …

Effect of relative air humidity on the flowability of lactose powders

…, F Boschini, V Delaval, A Rescaglio, R Cloots… - Journal of Drug Delivery …, 2016 - Elsevier
… Afterward, we show that the relative humidity range that optimizes … relative humidity, the
apparition of electric charges inside the bulk induces cohesive forces. For higher relative humidity

Micromechanics of diffuse axonal injury: influence of axonal orientation and anisotropy

RJH Cloots, JAW Van Dommelen, T Nyberg… - … and modeling in …, 2011 - Springer
Multiple length scales are involved in the development of traumatic brain injury, where the
global mechanics of the head level are responsible for local physiological impairment of brain …

Activation of goblet-cell stress sensor IRE1β is controlled by the mucin chaperone AGR2

E Cloots, P Guilbert, M Provost, L Neidhardt… - The EMBO …, 2023 - embopress.org
Intestinal goblet cells are secretory cells specialized in the production of mucins, and as
such are challenged by the need for efficient protein folding. Goblet cells express Inositol-…

TiO 2 multilayer thick films (up to 4 µm) with ordered mesoporosity: influence of template on the film mesostructure and use as high efficiency photoelectrode in DSSCs

J Dewalque, R Cloots, F Mathis, O Dubreuil… - Journal of Materials …, 2011 - pubs.rsc.org
… porosity, two different relative humidity (RH) conditions have … films, known as wormlike, the
relative humidity (RH) in the dip-… films, known as gridlike, the relative humidity (RH) in the dip-…

[CITATION][C] Bracke 824 KR, Zuyderduyn S, Dentener MA, Brusselle GG, Hiemstra PS, and Wouters EF. 825 Enhanced pulmonary leptin expression in patients with …

JH Vernooy, NE Drummen, RJ van Suylen, RH Cloots… - Thorax, 2009

[CITATION][C] 1026 Hakvoort TB, Lamers WH, and Kohler SE

RH Cloots, S Sankaranarayanan, CC de Theije… - Ablation of Arg1 in hematopoietic …