[HTML][HTML] Focus on hypoxia-related pathways in pediatric osteosarcomas and their druggability

…, B Lhermitte, M Messé, E Guérin, N Weingertner… - Cells, 2020 - mdpi.com
Osteosarcoma is the most frequent primary bone tumor diagnosed during adolescence and
young adulthood. It is associated with the worst outcomes in the case of poor response to …

Immune-desert tumor microenvironment in thoracic SMARCA4-deficient undifferentiated tumors with limited efficacy of immune checkpoint inhibitors

J Gantzer, G Davidson, B Vokshi, N Weingertner… - The …, 2022 - academic.oup.com
… expression profiling from SMARCA4-UT (n = 12), SMARCA4-deficient NSCLC (n = 4),
NOS NSCLC (n = 10), and unclassified thoracic sarcoma (UTS; n = 5) were downloaded from …

[HTML][HTML] NFATc2-rearranged sarcomas: clinicopathologic, molecular, and cytogenetic study of 7 cases with evidence of AGGRECAN as a novel diagnostic marker

…, M Karanian, A Meurgey, S Le Guellec, N Weingertner… - Modern Pathology, 2020 - Elsevier
NFATc2-rearranged sarcomas (NFATc2-Sarcomas) are infrequent round cell tumors
characterized by EWSR1-NFATc2 fusions and FUS-NFATc2 fusions. Although our knowledge on …

Superficial CD34‐positive fibroblastic tumor and PRDM10‐rearranged soft tissue tumor are overlapping entities: a comprehensive study of 20 cases

…, C Charon‐Barra, D Geneste, N Weingertner… - …, 2021 - Wiley Online Library
… following revision for this study as SCD34FT (n = 1) and PRDM10-STT (n = 3). In seven
cases, a … features) of SCD34FT (n = 3), MIFS (n = 2) and PHAT (n = 2) was rendered and …

Germ-line exon 21 EGFR mutations, V843I and P848L, in nonsmall cell lung cancer patients

…, E Guerin, B Mennecier, N Weingertner… - European …, 2014 - Eur Respiratory Soc
Somatic epidermal growth factor receptor (EGFR) mutations are now routinely integrated in
the molecular diagnosis of nonsmall cell lung cancers (NSCLC)[ 1, 2]. Thus, germ-line EGFR …

Cutaneous manifestations in patients with coronavirus disease 2019: clinical and histological findings

…, MP Chenard, M Mitcov, S Mayeur, N Weingertner - Human Pathology, 2021 - Elsevier
The clinical spectrum of coronavirus disease 2019 is getting wider with the exponential
increase of patients worldwide. Initially described with flu-like symptoms, variable cutaneous …

SMARCA4‐deficient rhabdoid tumours show intermediate molecular features between SMARCB1‐deficient rhabdoid tumours and small cell carcinomas of the ovary …

…, MP Castex, A Brouchet, N Weingertner… - The Journal of …, 2021 - Wiley Online Library
… expression analysis of ECRT SMARCA4 (n = 4) versus ECRT SMARCB1 (n = 19), resulting
in … S6), and between ECRT SMARCA4 (n = 4) and SCCOHT (n = 11), resulting in 269 genes …

Aggressive digital papillary adenocarcinoma: a clinicopathological study of 19 cases

N Weingertner, A Gressel, M Battistella… - Journal of the American …, 2017 - Elsevier
… (n = 1) or amputation (n = 2),2, 20 as our above-mentioned patient, and nevertheless
developed metastases 3 to 11 years after initial surgery. It is therefore very important to propose …

Adequately defining tumor cell proportion in tissue samples for molecular testing improves interobserver reproducibility of its assessment

B Lhermitte, C Egele, N Weingertner, D Ambrosetti… - Virchows Archiv, 2017 - Springer
Gene mutation status assessment of tumors has become standard practice in diagnostic
pathology. This is done using samples comprising tumor cells but also non-tumor cells, which …

Engineering Novel 3D Models to Recreate High‐Grade Osteosarcoma and its Immune and Extracellular Matrix Microenvironment

…, S Foppolo, C Nazon, N Weingertner… - Advanced …, 2022 - Wiley Online Library
… Cell population doubling time was determined using the following equation: doubling time
(days) = ln2(t−t 0 )/ln(N t /N 0 ), where t−t 0 is the time of exponential growth, N t and N 0 are …