Field walking tests are commonly employed to evaluate exercise capacity, assess prognosis
and evaluate treatment response in chronic respiratory diseases. In recent years, there has …

This systematic review examined the measurement properties of the 6-min walk test (6MWT),
incremental shuttle walk test (ISWT) and endurance shuttle walk test (ESWT) in adults with …

Background: Limb muscle dysfunction is prevalent in chronic obstructive pulmonary disease
(COPD) and it has important clinical implications, such as reduced exercise tolerance, …

… Pulse amplitudes greater than 100 mA may lead to intolerable muscle discomfort. Some
individuals are unable to tolerate NMES even at lower stimulus amplitudes and gains in …

… MA Spruit is the principal investigator of this trial. YMJ Goërtz, M. Van Herck, DJA Janssen
and MA Spruit drafted the manuscript. All authors critically reviewed and revised the …

Quantification of physical activities in daily life in patients with chronic obstructive pulmonary
disease has increasing clinical interest. However, detailed comparison with healthy …

Rationale: Pulmonary rehabilitation (PR) has demonstrated physiological, symptom-reducing,
psychosocial, and health economic benefits for patients with chronic respiratory diseases, …

Rationale: Comorbidities contribute to disease severity and mortality in patients with chronic
obstructive pulmonary disease (COPD). Comorbidities have been studied individually and …

… Spruit, Jörg Vehreschild, Bob Siegerink … Conflict of interest: MA Spruit reports grants
from the Netherlands Lung Foundation and Stichting Astma Bestrijding, and grants and …

… Spruit PhD a , Miriam TJ Groenen MSc a , Emiel FM Wouters PhD, MD a b , Daisy JA Janssen
PhD, … DJ Janssen, MA Spruit, JM Schols, EF Wouters … JM Gore, CJ Brophy, MA Greenstone …