Airway remodeling and inflammation in symptomatic infants with reversible airflow obstruction

S Saglani, K Malmström, AS Pelkonen… - American journal of …, 2005 - atsjournals.org
Rationale: We hypothesized that the epithelial reticular basement membrane (RBM) thickening
and eosinophilic inflammation characteristic of asthma would be present in symptomatic …

Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial

SE Dahlén, K Malmstrom… - American journal of …, 2002 - atsjournals.org
Leukotriene antagonists block the proinflammatory actions of leukotrienes (LT) and have been
introduced as new treatments for asthma. Conventional therapy with glucocorticosteroids …

Remodeling, inflammation and airway responsiveness in early childhood asthma

K Malmström, AS Pelkonen… - Current opinion in allergy …, 2013 - journals.lww.com
… Bisgaard H, Bonnelykke K, Sleiman PMA, et al. Chromosome 17q21 gene variants are
associated with asthma and exacerbations but not atopy in early childhood. Am J Respir …

Assessment of problematic severe asthma in children

…, E Baraldi, C Pedroletti, A Barbato, K Malmström… - 2011 - Eur Respiratory Soc
Malmström: Dept of Allergy, Helsinki University Central Hospital, Helsinki, Finland. P.
Pohunek: Charles University, 2nd … Pedroletti, K. Malmström, RJM Middelveld and KH Carlsen. …

Longitudinal follow-up of bronchial inflammation, respiratory symptoms, and pulmonary function in adolescents after repair of esophageal atresia with …

K Malmström, J Lohi, H Lindahl, A Pelkonen… - The Journal of …, 2008 - Elsevier
OBJECTIVE: To characterize symptoms, pulmonary function tests (PFT) and bronchial
responsiveness (BR) in adolescents after repaired esophageal atresia with tracheoesophageal …

Repaired oesophageal atresia: respiratory morbidity and pulmonary function in adults

S Sistonen, P Malmberg, K Malmström… - European …, 2010 - Eur Respiratory Soc
Although after oesophageal atresia (OA) repair in infancy, respiratory problems are common,
their natural history remains unclear. We assessed morbidity, pulmonary function (PF), and …

Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma: a randomized, controlled trial

K Malmstrom, G Rodriguez-Gomez… - Annals of internal …, 1999 - acpjournals.org
Background: Oral leukotriene receptor antagonists have been shown to have efficacy in
chronic asthma. Objective: To compare the clinical benefit of montelukast, a once-daily oral …

Lung function, airway remodelling and inflammation in symptomatic infants: outcome at 3 years

K Malmström, AS Pelkonen, LP Malmberg, S Sarna… - Thorax, 2011 - thorax.bmj.com
Background Relationships between early deficits of lung function, infant airway pathology
and outcome in symptomatic infants are unclear. A study was undertaken to determine the …

Concomitant montelukast and loratadine as treatment for seasonal allergic rhinitis: a randomized, placebo-controlled clinical trial

EO Meltzer, K Malmstrom, S Lu, BM Prenner… - Journal of allergy and …, 2000 - Elsevier
Background: Nasal challenge studies have suggested histamine and cysteinyl leukotrienes
are important proinflammatory mediators in allergic rhinitis. This study was designed to …

Montelukast for treating seasonal allergic rhinitis: a randomized, double‐blind, placebo‐controlled trial performed in the spring

G Philip, K Malmstrom, FC Hampel Jr… - Clinical & …, 2002 - Wiley Online Library
Background Cysteinyl leukotrienes are important proinflammatory mediators believed to
have a role in allergic rhinitis. Objective This multicentre, randomized, double‐blind, placebo‐ …