User profiles for J. Lager

Joanne J Lager

Chief Medical Officer, iTeos Therapeutics
Verified email at iteostherapeutics.com
Cited by 1902

Janus kinase-2 inhibitor fedratinib in patients with myelofibrosis previously treated with ruxolitinib (JAKARTA-2): a single-arm, open-label, non-randomised, phase 2 …

…, S Zweegman, M Talpaz, J Lager… - The Lancet …, 2017 - thelancet.com
J-JK reports personal fees and non-financial support from Novartis and Shire, and grants
from AOP Orphan. RVT reports participation in advisory boards and speaker bureaus for Incyte …

A Phase II, open-label study evaluating pazopanib in patients with recurrent ovarian cancer

…, GM Matthys, B Ma, JP Hodge, JJ Lager - Gynecologic …, 2010 - Elsevier
OBJECTIVE: The progression-free and median survival of patients with advanced ovarian
cancer has not appreciably improved over the last decade. Novel targeted therapies, …

Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models

…, S Witzel, Q Yu, YA Zhang, G Zheng, J Lager… - Science translational …, 2021 - science.org
Local immunotherapy ideally stimulates immune responses against tumors while avoiding
toxicities associated with systemic administration. Current strategies for tumor-targeted, gene-…

[PDF][PDF] Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies

…, DF Kisor, JJ Lager, C Stephens, J Levin… - Journal of Clinical …, 2005 - researchgate.net
Purpose A phase I study was conducted to determine the maximum-tolerated dose (MTD),
toxicity profile, and pharmacokinetics of a novel purine nucleoside, nelarabine, a soluble …

Ethnic and gender differences in psychosocial factors, glycemic control, and quality of life among adult type 2 diabetic patients

R Misra, J Lager - Journal of Diabetes and its Complications, 2009 - Elsevier
Objective To examine ethnic and gender differences in psychosocial factors, eg, social
support and acceptance of the disease, knowledge levels, perceived difficulty in adherence …

A phase I study of the pharmacokinetic and safety profiles of oral pazopanib with a high‐fat or low‐fat meal in patients with advanced solid tumors

…, CJ Sweeney, JP Hodge, JJ Lager… - Clinical …, 2010 - Wiley Online Library
Pazopanib is an oral angiogenesis inhibitor of vascular endothelial growth factor (VEGF)
receptor, platelet‐derived growth factor receptor, and cytokine receptor. This open‐label, …

An evaluation of the drug interaction potential of pazopanib, an oral vascular endothelial growth factor receptor tyrosine kinase inhibitor, using a modified …

…, T Arumugham, Y Xu, CF Xu, J Lager… - Clinical …, 2010 - Wiley Online Library
Pazopanib, an oral inhibitor of vascular endothelial growth factor receptor, platelet‐derived
growth factor receptor, and c‐kit kinases, inhibits multiple cytochrome P450 (CYP450) …

Phase I dose-escalation study of the PI3K/mTOR inhibitor voxtalisib (SAR245409, XL765) plus temozolomide with or without radiotherapy in patients with high-grade …

…, N Mohile, JJ Lager, AD Laird, J Tang, J Jiang… - Neuro …, 2015 - academic.oup.com
Background This phase I study aimed to evaluate safety, maximum tolerated dose,
pharmacokinetics, pharmacodynamics, and preliminary efficacy of voxtalisib (SAR245409, XL765), a …

Electronic Structure and Luminescence of Quasi-Freestanding MoS2 Nanopatches on Au(111)

N Krane, C Lotze, JM Läger, G Reecht, KJ Franke - Nano Letters, 2016 - ACS Publications
Monolayers of transition metal dichalcogenides are interesting materials for optoelectronic
devices due to their direct electronic band gaps in the visible spectral range. Here, we grow …

[HTML][HTML] Catchbasin technology overview and assessment

JA Lager, WG Smith, G Tchobanoglous - 1977 - books.google.com
Lager, William G. Smith, and George Tchobanoglous Metcalf & Eddy, Inc., Palo Alto,
California 94303 in association with … Lager, Project Director, and William G. Smith, Project …