Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis

…, TR Walker, R Duffin, M Gray, E Crescenzi… - Nature medicine, 2006 - nature.com
Apoptosis is essential for clearance of potentially injurious inflammatory cells and subsequent
efficient resolution of inflammation. Here we report that human neutrophils contain …

The neutrophil gelatinase-associated lipocalin (NGAL), a NF-κB-regulated gene, is a survival factor for thyroid neoplastic cells

…, A Lavorgna, E Crescenzi… - Proceedings of the …, 2008 - National Acad Sciences
NF-κB is constitutively activated in primary human thyroid tumors, particularly in those of
anaplastic type. The inhibition of NF-κB activity in the human anaplastic thyroid carcinoma cell …

[HTML][HTML] Glutamine metabolism in cancer stem cells: a complex liaison in the tumor microenvironment

F Pacifico, A Leonardi, E Crescenzi - International Journal of Molecular …, 2023 - mdpi.com
In this review we focus on the role of glutamine in control of cancer stem cell (CSC) fate. We
first provide an overview of glutamine metabolism, and then summarize relevant studies …

[HTML][HTML] NGAL as a potential target in tumor microenvironment

E Crescenzi, A Leonardi, F Pacifico - International Journal of Molecular …, 2021 - mdpi.com
The signaling network between cancer and stromal cells plays a crucial role in tumor
microenvironment. The fate of tumor progression mainly depends on the huge amount of …

Oligonucleotide aptamers against tyrosine kinase receptors: Prospect for anticancer applications

S Camorani, E Crescenzi, M Fedele… - Biochimica et Biophysica …, 2018 - Elsevier
Transmembrane receptor tyrosine kinases (RTKs) play crucial roles in cancer cell proliferation,
survival, migration and differentiation. Area of intense research is searching for effective …

Renin-angiotensin-aldosterone system in patients with sleep apnoea: prevalence of primary aldosteronism

…, L Zinnamosca, E Crescenzi… - Journal of the Renin …, 2010 - journals.sagepub.com
Obstructive sleep apnoea (OSA) is a sleep disorder characterized by recurrent episodes of
oxygen desaturation during sleep, representing an independent risk factor for cardiovascular …

Photodynamic therapy with indocyanine green complements and enhances low-dose cisplatin cytotoxicity in MCF-7 breast cancer cells

E Crescenzi, L Varriale, M Iovino, A Chiaviello… - Molecular cancer …, 2004 - AACR
Objective: We investigated the effects of photodynamic therapy (PDT) combined with low-dose
chemotherapy on breast cancer cells. Photodynamic treatment was administered by …

Nuclear factor-κB contributes to anaplastic thyroid carcinomas through up-regulation of miR-146a

F Pacifico, E Crescenzi, S Mellone… - The Journal of …, 2010 - academic.oup.com
Context: Micro-RNAs (miRNAs) have been recently involved in the modulation of several
biological activities including cancer. Many human tumors show deregulated expression of …

Targeted gene transfer in eucaryotic cells by dye-assisted laser optoporation

G Palumbo, M Caruso, E Crescenzi, MF Tecce… - … of Photochemistry and …, 1996 - Elsevier
The blue beam of an Argon laser (488 nm) has been focused on the cell membrane in the
presence of phenol-red, an usual component of cell culture media, through a 100 × objective. …

[HTML][HTML] Oncogenic and anti-apoptotic activity of NF-κB in human thyroid carcinomas

F Pacifico, C Mauro, C Barone, E Crescenzi… - Journal of Biological …, 2004 - ASBMB
Thyroid cancer includes three types of carcinomas classified as differentiated thyroid carcinomas
(DTC), medullary thyroid carcinomas, and undifferentiated carcinomas (UTC). DTC and …