Polyhydroxyalkanoate (PHA): Applications in drug delivery and tissue engineering

E Elmowafy, A Abdal-Hay, A Skouras… - Expert review of …, 2019 - Taylor & Francis
Introduction: The applications of naturally obtained polymers are tremendously increased
due to them being biocompatible, biodegradable, environmentally friendly and renewable in …

Chylothorax: diagnostic approach

V Skouras, I Kalomenidis - Current opinion in pulmonary medicine, 2010 - journals.lww.com
Chylothorax is the accumulation of chyle into the pleural cavity usually due to thoracic duct
leak and should be suspected not only in patients with milky effusions but also in the …

[HTML][HTML] Midclavicular fracture: not just a trivial injury: current treatment options

G Schiffer, C Faymonville, E Skouras… - Deutsches Ärzteblatt …, 2010 - ncbi.nlm.nih.gov
Background Conservative treatment was long recommended for midclavicular fractures
because of the excellent results that were reported in the 1960’s and 70’s. Recently, however, …

OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation

…, RB Barrow, RD Altman, DB Skouras… - Proceedings of the …, 2018 - National Acad Sciences
Activation of the NLRP3 inflammasome induces maturation of IL-1β and IL-18, both validated
targets for treating acute and chronic inflammatory diseases. Here, we demonstrate that …

An audit of the use of laser Doppler imaging (LDI) in the assessment of burns of intermediate depth

SA Pape, CA Skouras, PO Byrne - Burns, 2001 - Elsevier
This is the first report of an evaluation of the use of a laser Doppler imager (LDI) scanner in
the assessment of burn depth in patients. It is based on a 6-month, prospective audit of 76 …

A tug of war: Overnight versus intraday expected returns

D Lou, C Polk, S Skouras - Journal of Financial Economics, 2019 - Elsevier
We link investor heterogeneity to the persistence of the overnight and intraday components
of returns. We document strong overnight and intraday firm-level return continuation along …

The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer's disease

…, S Hosseini, C Marchetti, DB Skouras… - Proceedings of the …, 2020 - National Acad Sciences
Numerous studies demonstrate that neuroinflammation is a key player in the progression of
Alzheimer’s disease (AD). Interleukin (IL)-1β is a main inducer of inflammation and therefore …

Computational design of actuated deformable characters

M Skouras, B Thomaszewski, S Coros… - ACM Transactions on …, 2013 - dl.acm.org
We present a method for fabrication-oriented design of actuated deformable characters that
allows a user to automatically create physical replicas of digitally designed characters using …

Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial

…, MCP Cleophas, CL Scribner, DB Skouras… - The Lancet …, 2020 - thelancet.com
Background Gout flares are driven by interleukin (IL)-1β. Dapansutrile inhibits the NLRP3
inflammasome and subsequent activation of IL-1β. In this study we aimed to investigate the …

Two-scale topology optimization with microstructures

B Zhu, M Skouras, D Chen, W Matusik - ACM Transactions on Graphics …, 2017 - dl.acm.org
In this article, we present a novel two-scale framework to optimize the structure and the
material distribution of an object given its functional specifications. Our approach utilizes multi-…