Coronavirus disease 2019 (COVID-19) has spread rapidly throughout the globe. It is associated
with significant mortality, particularly in at-risk groups with poor prognostic features at …

Flexible bronchoscopy is commonly performed by respiratory physicians and is the gold
standard for directly visualising the airways, allowing for numerous diagnostic and therapeutic …

As our practice expands, relocation of appropriately triaged pulmonary interventional
procedures including rigid bronchoscopy that were previously assigned to a traditional operating …

Background Multidrug-resistant tuberculosis (MDR-TB) is an increasing challenge to health
services globally. Although new drugs are in development, current guidelines still …

Background Acute respiratory distress syndrome (ARDS) is a life-threatening condition
characterised by pulmonary oedema, respiratory failure and severe inflammation. ARDS is …

The coagulation cascade plays a central role in the pathogenesis of fibroproliferative lung
diseases such as the acute respiratory distress syndrome (ARDS) and idiopathic pulmonary …

PAR 1 plays a central role in mediating the interplay between coagulation and inflammation,
but its role in regulating acute neutrophilic inflammation is unknown. We report that …

Objective— Sclerostin (SOST) has been identified as an important regulator of bone formation;
however, it has not been previously implicated in arterial disease. The aim of this study …

Neutrophil migration into the airways is an important process to fight infection and is mediated
by cell adhesion molecules. The intercellular adhesion molecules, ICAM-1 (CD54) and …

Twelve dogs with poorly controlled idiopathic epilepsy were entered into a prospective,
open-label, noncomparative study. Oral zonisamide was administered as an additional therapy …