Thrombin is a multifunctional serine protease generated at the site of vascular injury that
transforms fibrinogen into fibrin, activates blood platelets and elicits multiple effects on a variety …

The ability of a virus to spread between individuals, its replication capacity and the clinical
course of the infection are macroscopic consequences of a multifaceted molecular interaction …

Diabetes mellitus is one of the major risk factors for cognitive dysfunction. The pathogenesis
of brain impairment caused by chronic hyperglycemia is complex and includes …

Background Several small studies on patients with COVID-19 and haematological
malignancies are available showing a high mortality in this population. The Italian Hematology …

Neutrophils use immunoglobulins to clear antigen, but their role in immunoglobulin production
is unknown. Here we identified neutrophils around the marginal zone (MZ) of the spleen, …

Uterine leiomyomas, or fibroids, are benign tumors that affect millions of women worldwide
and that can cause considerable morbidity. To study the genetic basis of this tumor type, we …

… For immunoelectron microscopy cells were fixed, after two washes in 0.1 M cacodylate
buffer, with 3% paraformaldehyde in 0.1 M cacodylate buffer for 2 h. Then, they were embedded …

A dense mucus layer in the large intestine prevents inflammation by shielding the underlying
epithelium from luminal bacteria and food antigens. This mucus barrier is organized around …

Background & Aims: Normal and neoplastic cells release microvesicles, whose effects on
the immune system still need to be elucidated. Because human colorectal cancer cells are …

… and consultant Mary Gentile challenges the assumptions about … The book is inspired by a
program Gentile launched at the … of ethical dilemmas, Gentile empowers business leaders with …