User profiles for J. Sont

Jacob K. Sont

Associate professor, Leiden University Medical Center
Verified email at lumc.nl
Cited by 9705

Illness perceptions and COPD: an emerging field for COPD patient management

…, LD Cameron, JK Sont, KF Rabe, J Weinman - Journal of …, 2008 - Taylor & Francis
Objective. Patients with chronic obstructive pulmonary disease have perceptions of their
illness and its management that determine their coping behaviors (eg, adherence, self-…

Assessing the effect of deep inhalation on airway calibre: a novel approach to lung function in bronchial asthma and COPD

R Pellegrino, PJ Sterk, JK Sont… - European Respiratory …, 1998 - Eur Respiratory Soc
… Froeb HF, Mead J. Relative hysteresis of the dead space and lung in vivo. … Gayard P,
Orehek J, Grimaud C, Charpin J. Bronchoconstrictor effects of a deep inspiration in patients with …

Exacerbations in adults with asthma: a systematic review and external validation of prediction models

…, M Timp, KF Chung, AR Sousa, JK Sont… - The Journal of Allergy …, 2018 - Elsevier
Background Several prediction models assessing future risk of exacerbations in adult patients
with asthma have been published. Applicability of these models is uncertain because their …

Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment

JK Sont, LNA Willems, EH Bel… - American journal of …, 1999 - atsjournals.org
According to international guidelines, the level and adjustment of antiinflammatory treatment
for asthma are based solely on symptoms and lung function. We investigated whether a …

Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial

…, D Farge, JK Sont, K Naraghi, Z Marjanovic, J Larghero… - Jama, 2014 - jamanetwork.com
Importance High-dose immunosuppressive therapy and autologous hematopoietic stem cell
transplantation (HSCT) have shown efficacy in systemic sclerosis in phase 1 and small …

Monocyte chemoattractant protein 1, interleukin 8, and chronic airways inflammation in COPD

…, JK Sont, A van Schadewijk, J Stolk… - The Journal of …, 2000 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is one of the most common causes of death,
with cigarette smoking among the main risk factors. Hallmarks of COPD include chronic …

Transforming Growth Factor β1 and Recruitment of Macrophages and Mast Cells in Airways in Chronic Obstructive Pulmonary Disease

WI de Boer, A van SCHADEWIJK, JK Sont… - American journal of …, 1998 - atsjournals.org
Chronic airways inflammation is one of the features of chronic obstructive pulmonary
disease (COPD). We demonstrated previously that bronchiolar epithelium in COPD contains …

Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids.

JK Sont, J Han, JM Van Krieken, CE Evertse, R Hooijer… - Thorax, 1996 - thorax.bmj.com
BACKGROUND: Current guidelines on the management of asthma advocate the use of anti-inflammatory
treatment in all but mild disease. They define disease control in terms of …

Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: a randomized trial

…, HM Boezen, NHT Ten Hacken, JK Sont… - Annals of internal …, 2009 - acpjournals.org
Background: Inhaled corticosteroids (ICSs) and long-acting β 2 -agonists (LABAs) are used
to treat moderate to severe chronic obstructive pulmonary disease (COPD). Objective: To …

Internet-based self-management plus education compared with usual care in asthma: a randomized trial

…, PJ Sterk, J Kievit, WJJ Assendelft, JK Sont… - Annals of Internal …, 2009 - acpjournals.org
Background: The Internet may support patient self-management of chronic conditions, such
as asthma. Objective: To evaluate the effectiveness of Internet-based asthma self-…