Some new, simple and efficient stereological methods and their use in pathological research and diagnosis
Stereology is a set of simple and efficient methods for quantitation of three‐dimensional
microscopic structures which is specifically tuned to provide reliable data from sections. Within …
microscopic structures which is specifically tuned to provide reliable data from sections. Within …
The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis
The new stereological methods for correct and efficient sampling and sizing of cells and
other particles are reviewed. There is a hierarchy of methods starting from the simplest where …
other particles are reviewed. There is a hierarchy of methods starting from the simplest where …
Hyperglycemic pseudohypoxia and diabetic complications
…, KS Hasan, Y Ido, T Kawamura, JR Nyengaard… - Diabetes, 1993 - Am Diabetes Assoc
Vasodilation and increased blood flow are characteristic early vascular responses to acute
hyperglycemia and tissue hypoxia. In hypoxic tissues these vascular changes are linked to …
hyperglycemia and tissue hypoxia. In hypoxic tissues these vascular changes are linked to …
Glomerular number and size in relation to age, kidney weight, and body surface in normal man
JR Nyengaard, TF Bendtsen - The Anatomical Record, 1992 - Wiley Online Library
The number and size of glomeruli in normal, mature human kidneys were estimated by a
direct and unbiased stereological method, the fractionator. The number was 617,000 on …
direct and unbiased stereological method, the fractionator. The number was 617,000 on …
[PDF][PDF] Dynamics of cell generation and turnover in the human heart
…, T Malm, M Andrä, R Jashari, JR Nyengaard… - Cell, 2015 - cell.com
The contribution of cell generation to physiological heart growth and maintenance in
humans has been difficult to establish and has remained controversial. We report that the full …
humans has been difficult to establish and has remained controversial. We report that the full …
Marked loss of myelinated nerve fibers in the human brain with age
L Marner, JR Nyengaard, Y Tang… - Journal of comparative …, 2003 - Wiley Online Library
The white matter is the structure of the brain that declines most with age—almost 30%, but
little is known about the age‐effect on the fibers that constitute the white matter. In the present …
little is known about the age‐effect on the fibers that constitute the white matter. In the present …
[HTML][HTML] Maternal protein restriction suppresses the newborn renin-angiotensin system and programs adult hypertension in rats
LL Woods, JR Ingelfinger, JR Nyengaard, R Rasch - Pediatric research, 2001 - nature.com
Restriction of maternal protein intake during rat pregnancy produces offspring that are
hypertensive in adulthood, but the mechanisms are not well understood. Our purpose was to …
hypertensive in adulthood, but the mechanisms are not well understood. Our purpose was to …
The number of alveoli in the human lung
The number of alveoli is a key structural determinant of lung architecture. A design-based
stereologic approach was used for the direct and unbiased estimation of alveolar number in …
stereologic approach was used for the direct and unbiased estimation of alveolar number in …
[HTML][HTML] RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system
…, MB Hovgaard, A Schmitz, JR Nyengaard… - Molecular Therapy, 2006 - cell.com
This work introduces a novel chitosan-based siRNA nanoparticle delivery system for RNA
interference in vitro and in vivo. The formation of interpolyelectrolyte complexes between …
interference in vitro and in vivo. The formation of interpolyelectrolyte complexes between …
Tissue shrinkage and unbiased stereological estimation of particle number and size
KA Dorph‐Petersen, JR Nyengaard… - Journal of …, 2001 - Wiley Online Library
This paper is a review of the stereological problems related to the unbiased estimation of
particle number and size when tissue deformation is present. The deformation may occur …
particle number and size when tissue deformation is present. The deformation may occur …