Abstract
We present the case of a 72-year-old male with chronic phase myeloid leukemia. Elevation of the pulmonary artery pressure due to nilotinib therapy was noted. This effect on pulmonary artery pressure was nilotinib dose dependent.
MeSH terms
-
Aged
-
Antineoplastic Agents / administration & dosage
-
Antineoplastic Agents / adverse effects*
-
Antineoplastic Agents / therapeutic use
-
Echocardiography, Doppler
-
Familial Primary Pulmonary Hypertension
-
Humans
-
Hypertension, Pulmonary / chemically induced*
-
Hypertension, Pulmonary / diagnosis*
-
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / complications
-
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy
-
Male
-
Natriuretic Peptide, Brain / blood
-
Peptide Fragments / blood
-
Pyrimidines / administration & dosage
-
Pyrimidines / adverse effects*
-
Pyrimidines / therapeutic use
Substances
-
Antineoplastic Agents
-
Peptide Fragments
-
Pyrimidines
-
pro-brain natriuretic peptide (1-76)
-
Natriuretic Peptide, Brain
-
nilotinib