Abstract
This article covers the airway tree with respect to anatomy, pathology, and physiology. The anatomic portion discusses various primate groups so as to help investigators understand similarities and differences between animal models. An emphasis is on distal airway findings. The pathology section focuses on the inflammatory responses that occur in proximal and distal airways. The physiologic review brings together the anatomic and pathologic components to the functional state and proposes ways to evaluate the small airways in patients with asthma.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Asthma* / pathology
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Asthma* / physiopathology
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Bronchi* / anatomy & histology
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Bronchi* / pathology
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Bronchi* / physiology
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Bronchioles* / anatomy & histology
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Bronchioles* / pathology
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Bronchioles* / physiology
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Disease Models, Animal
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Humans
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Inflammation / pathology
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Inflammation / physiopathology
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Mice
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Rats
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Respiratory System / anatomy & histology
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Respiratory System / pathology
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Respiratory System / physiopathology
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Trachea* / anatomy & histology
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Trachea* / pathology
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Trachea* / physiology