Recurrent portopulmonary hypertension after liver transplantation: management with epoprostenol and resolution after retransplantation

D H Kett; R C Acosta; M A Campos; M J Rodriguez; A A Quartin; R M Schein

doi:10.1053/jlts.2001.25358

Recurrent portopulmonary hypertension after liver transplantation: management with epoprostenol and resolution after retransplantation

Liver Transpl. 2001 Jul;7(7):645-8. doi: 10.1053/jlts.2001.25358.

Authors

D H Kett¹, R C Acosta, M A Campos, M J Rodriguez, A A Quartin, R M Schein

Affiliation

¹ Divisions of Pulmonary and Critical Care Medicine, Department of Medicine, University of Miami School of Medicine, Miami, FL, USA. dkett@med.miami.edu

PMID: 11460234
DOI: 10.1053/jlts.2001.25358

Abstract

We report a case of portopulmonary hypertension in which the pulmonary hypertension resolved after initial orthotopic liver transplantation. Portopulmonary hypertension recurred when the transplanted liver failed and again resolved after a second liver transplantation. Intravenous epoprostenol was administered perioperatively to control the pulmonary hypertension in both instances.

Publication types

Case Reports

MeSH terms

Antihypertensive Agents / therapeutic use*
Epoprostenol / therapeutic use*
Hemodynamics
Humans
Hypertension, Portal / drug therapy
Hypertension, Portal / etiology
Hypertension, Portal / physiopathology
Hypertension, Portal / therapy*
Hypertension, Pulmonary / drug therapy
Hypertension, Pulmonary / etiology
Hypertension, Pulmonary / physiopathology
Hypertension, Pulmonary / therapy*
Liver Transplantation / adverse effects*
Male
Middle Aged
Recurrence
Reoperation
Treatment Failure

Substances

Antihypertensive Agents
Epoprostenol