Pulmonary Mucosa-associated Lymphoid Tissue (MALT) Lymphoma in Sjögren's Syndrome Showing Only the LIP Pattern Radiologically

Yasutaka Watanabe; Shinichiro Koyama; Chihiro Miwa; Shinya Okuda; Yoshihiko Kanai; Kenji Tetsuka; Mitsuhiro Nokubi; Yoh Dobashi; Yoshinori Kawabata; Yoshinobu Kanda; Shunsuke Endo

doi:10.2169/internalmedicine.51.6242

CASE REPORTS

Pulmonary Mucosa-associated Lymphoid Tissue (MALT) Lymphoma in Sjögren's Syndrome Showing Only the LIP Pattern Radiologically

Yasutaka Watanabe, Shinichiro Koyama, Chihiro Miwa, Shinya Okuda, Yoshihiko Kanai, Kenji Tetsuka, Mitsuhiro Nokubi, Yoh Dobashi, Yoshinori Kawabata, Yoshinobu Kanda, Shunsuke Endo

Author information

Yasutaka Watanabe
Division of Pulmonary Medicine, Saitama Medical Center, Jichi Medical University, Japan
Shinichiro Koyama
Division of Pulmonary Medicine, Saitama Medical Center, Jichi Medical University, Japan
Chihiro Miwa
Division of Pulmonary Medicine, Saitama Medical Center, Jichi Medical University, Japan
Shinya Okuda
Division of Hematology, Saitama Medical Center, Jichi Medical University, Japan
Yoshihiko Kanai
Division of Thoracic Surgery, Saitama Medical Center, Jichi Medical University, Japan
Kenji Tetsuka
Division of Thoracic Surgery, Saitama Medical Center, Jichi Medical University, Japan
Mitsuhiro Nokubi
Division of Pathology, Saitama Medical Center, Jichi Medical University, Japan
Yoh Dobashi
Division of Pathology, Saitama Medical Center, Jichi Medical University, Japan
Yoshinori Kawabata
Division of Pathology, Saitama Cardiovascular and Respiratory Center, Japan
Yoshinobu Kanda
Division of Hematology, Saitama Medical Center, Jichi Medical University, Japan
Shunsuke Endo
Division of Thoracic Surgery, Saitama Medical Center, Jichi Medical University, Japan

Keywords: Sjögren's syndrome, mucosa-associated lymphoid tissue lymphoma, interstitial pneumonia, lung biopsy

JOURNAL OPEN ACCESS

2012 Volume 51 Issue 5 Pages 491-495

DOI https://doi.org/10.2169/internalmedicine.51.6242

Details

Abstract

A 49-year-old woman with a 20-year history of Sjögren's syndrome (SS) was incidentally found to have an abnormal chest X-ray along with dyspnea and desaturation. Chest CT findings showed multiple cystic shadows, ground glass opacity, and small nodule-like lymphocytic interstitial pneumonia (LIP), which have been previously reported. She was diagnosed by surgical lung biopsy to have mucosa-associated lymphoid tissue (MALT) lymphoma. It was difficult to detect the presence of lymphoma by the use of only CT findings. Pulmonary involvement of SS occurs in various forms so that SS patients with pulmonary involvement should undergo open biopsy to reach a definitive diagnosis.

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