Chest
Volume 144, Issue 1, July 2013, Pages 358-359
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Correspondence
Statins Reduce Lung Inflammation by Promoting the Clearance of Particulate Matter From Lung Tissues

https://doi.org/10.1378/chest.13-0496Get rights and content

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To the Editor

We read with interest the article by Miyata and colleagues1 (February 2013) in which the authors reported that lovastatin attenuates lung inflammation in a rabbit model by attenuating macrophage and neutrophil recruitment and activation. We outline here why this is such an important finding.

There is growing interest in the potential role of statins as adjunct therapy in COPD. Human and animal studies suggest that statins reduce both pulmonary and systemic inflammation, which is characterized by

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Financial/nonfinancial disclosures: The authors have reported to CHEST that no potential conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.

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