Chest
CorrespondenceStatins Reduce Lung Inflammation by Promoting the Clearance of Particulate Matter From Lung Tissues
Section snippets
To the Editor
We read with interest the article by Miyata and colleagues1 (February 2013) in which the authors reported that lovastatin attenuates lung inflammation in a rabbit model by attenuating macrophage and neutrophil recruitment and activation. We outline here why this is such an important finding.
There is growing interest in the potential role of statins as adjunct therapy in COPD. Human and animal studies suggest that statins reduce both pulmonary and systemic inflammation, which is characterized by
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Statins reduce ambient particulate matter-induced lung inflammation by promoting the clearance of particulate matter <10 μm from lung tissues
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Pharmacological actions of statins: potential utility in COPD
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Financial/nonfinancial disclosures: The authors have reported to CHEST that no potential conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.
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