Chest
Clinical InvestigationsExercise Training Decreases Ventilatory Requirements and Exercise-Induced Hyperinflation at Submaximal Intensities in Patients With COPD
Section snippets
Subjects
The 24 subjects participating in this study are a subgroup of the subjects previously described by Emtner et al.10 This subgroup had had satisfactory EELV assessments that allowed us to focus, for what we believe is the first time, on the specific effects of endurance exercise training on EELV and its potential contribution to exercise intolerance in patients with COPD. These patients did not differ in any of their pulmonary function data from the rest of the original population. The original
Results
Twenty-four subjects were involved in this study. Six of the 30 subjects in the report of Emtner et al10 were excluded because adequate IC measurements were not obtained. As there was no significant difference between the groups (ie, those receiving supplemental oxygen or air during the training) in terms of baseline pulmonary function, exercise tolerance, or ventilatory response, the groups were combined for further analysis (Table 1), although we utilized different symbols for the groups in
Discussion
In this article, we demonstrate that after exercise training, there is a marked increase in constant work endurance (almost 300% longer than pretraining; Table 2). This is associated with reduced dynamic hyperinflation during CWR exercise in the majority of subjects. Further, the reduction in dynamic hyperinflation was shown to be correlated with the reduced f. This is not surprising, as an acute effect of oxygen inhalation has been shown to reduce f and also to reduce dynamic hyperinflation.6
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