Chest
BronchoscopyTransbronchial Needle Aspiration in Diagnosing Intrathoracic Tuberculous Lymphadenitis
Section snippets
Materials and Methods
The role of TBNA in diagnosing isolated intrathoracic TB-LA was studied from 1992 through 2000 at a tertiary referral center for thoracic medicine and surgery. Patient enrollment was carried out from 1992 through 1997, and follow-ups were conducted during and after treatment until 2001. Prebronchoscopically, consecutively enrolled patients were required to have mediastinal/hilar lymphadenopathy of ≥ 10 mm seen on a chest radiograph or thoracic CT scan, a history of TB contact, tuberculin test
Results
Of the 98 patients who were initially included in the study, 14 patients who refused to undergo or were intolerant of FB were excluded. Of the 84 eligible patients with isolated hilar or mediastinal lymphadenopathy who were all found to be HIV-negative (63 male patients and 21 female patients; mean [± SD] age, 24.2 ± 7.1; age range, 12 to 74 years; age < 15 years, 41 patients), TB was confirmed in 76. These 76 patients constituted 2.5% of 3,038 patients with thoracic TB diagnosed at our
Discussion
In the diagnosis and staging of bronchogenic carcinoma, larger-caliber histology needles (18-gauge or 19-gauge) for TBNA have been reported to increase the yield over that of 21-gauge or 22-gauge needles,2,23,26 and also have been shown to overcome the rare occurrence of false-positive cytologic results.4,23,27,28 Nevertheless, cytology needles have been providing adequate accuracy in the diagnosis and staging of bronchogenic carcinoma.1,2,3,4
The histology needle, which is also capable of
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Cited by (78)
Intrathoracic tuberculosis: Role of interventional bronchoscopy in diagnosis
2023, Paediatric Respiratory ReviewsBronchoscopic sampling techniques in the era of technological bronchoscopy
2022, PulmonologyCitation Excerpt :American College of Chest Physician (ACCP) guidelines showed a sensitivity of 78% in the diagnosis and staging of non-small cell lung cancer, with a complication rate of 0.3%.46,47 It was also used for the diagnosis of sarcoidosis stage I and II and mediastinal tuberculosis (sensitivity of 72...79% and 65...100%, respectively %).27,48...50 Currently, cTBNA has been replaced by endobronchial ultrasound (EBUS)-guided TBNA: it includes an echobronchoscope (i.e., a bronchoscope with a convex probe at the distal end) and allows a real-time visualization of the lymph nodes and mediastinal vessels.
Bronchoscopic techniques in the management of patients with tuberculosis
2017, International Journal of Infectious DiseasesCitation Excerpt :TBLA diagnosis relies on smear microscopy and culture, in association with specific cytological and histological features (Navani et al., 2011; Eom et al., 2015). Conventional TBNA with both cytology (21-22 gauge) and histology (19 gauge) needles has been the first bronchoscopic technique to diagnose TBLA, showing a sensitivity of 65.0-100.0% and a specificity of 100.0%, with a good safety profile (Cetinkaya et al., 2002; Cetinkaya et al., 2004; De Wet et al., 2015; Bilaceroglu et al., 2004; Baran et al., 1996). With the implementation of endobronchial ultrasounds, EBUS-TBNA has become the standard for the diagnosis of a mediastinal lymphadenitis (Navani et al., 2011; Hassan et al., 2011; Ye et al., 2015; Li et al., 2015).
The additional role of Xpert MTB/RIF in the diagnosis of intrathoracic tuberculous lymphadenitis
2017, Journal of Infection and ChemotherapyCitation Excerpt :However, Xpert correctly identified only 2 out of 4 culture positive cases and therefore should be recommended as an adjunct to the conventional tests when EBUS-TBNA specimen are tested. The culture rate of 30.8% observed in this study is similar to the culture rates (21%–48%) of other studies [6,15–17]. The relatively low culture rates are likely to represent low bacillary load in intrathoracic TB lymph nodes.
Diagnostic Bronchoscopy
2015, Murray and Nadel's Textbook of Respiratory Medicine: Volume 1,2, Sixth EditionInterventional bronchoscopy in pediatric pulmonary tuberculosis
2023, Expert Review of Respiratory Medicine
This study was presented in part at the American Thoracic Society Congress (Chicago, IL; April 24 to 29, 1998), and was published in abstract form.
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Retired.
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Currently at the Department of Thoracic Surgery, Ege University School of Medicine, Izmir, Turkey.