Chest
Original ResearchPulmonary PhysiologyQuantification of Cardiorespiratory Fitness in Healthy Nonobese and Obese Men and Women
Section snippets
Materials and Methods
This is a retrospective study using subjects who took part in projects related to exercise and obesity in our laboratory.15, 16, 17, 18, 19, 20, 21 In accordance with the Institutional Review Board (University of Texas Southwestern Medical Center, STU 122010-108), all details of the experiments were discussed with the volunteers, and informed consent was obtained before participation. All subjects were selected using the same guidelines, were nonsmokers, and had the same exclusion criteria:
Results
Fifty-one men (11 nonobese, 40 obese) and 34 women (8 nonobese, 26 obese) comprised the cohort of 85 adults (Table 1).
There were no differences in maximal power output (W) or absolute o2peak (L/min) between the nonobese and obese (Table 2). However, o2peak relative to body mass (mL/min/kg) and LBM (mL/min/LBM) were lower (P < .01) in the obese. The effect of body mass on all traditional displays of o2peak are shown in Figure 1. o2peak (L/min) (Fig 1A) increases while o2peak (mL/min/kg) (Fig 1B)
Discussion
Our main findings are as follows: (1) Traditional methods of reporting o2peak (ie, L/min, mL/min/kg, mL/min/LBM) do not allow adequate assessment and quantification of CRF among obese and nonobese; (2) the use of a % predicted o2peak enables a graded assessment and quantification of CRF in obese, although care must be taken in selecting the most appropriate prediction equation, especially in women; (3) quantifying CRF in obesity is a complex and extremely important issue that requires careful
Acknowledgments
Author contributions: Dr Babb had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Dr Lorenzo: contributed to data collection, data processing and analysis, critical input, and the writing of the manuscript.
Dr Babb: contributed to planning the project, supervising and assisting in data collection, directing data processing and analysis, and the writing of the manuscript.
Financial/nonfinancial disclosures:
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2019, Respiratory Physiology and NeurobiologyCitation Excerpt :Peak power output (PPO) was defined as the highest power output a participant was able to sustain for ≥30-sec, while exercise endurance time was defined as the duration of loaded pedaling. The rate of O2 consumption at peak exercise (V̇O2,peak) was referenced to age, sex, height and ideal body mass predicted normal values (Lorenzo and Babb, 2012). Peak heart rate and PPO were referenced to their respective age, sex and height predicted normal values (Jones et al., 1985).
Funding/Support: This work was supported by the King Charitable Foundation Trust, American Lung Association, American Heart Association, The Research and Education Institute at Texas Health Resources, Cain Foundation, National Institutes of Health [HL096782], and Texas Health Presbyterian Hospital Dallas.
Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (http://www.chestpubs.org/site/misc/reprints.xhtml).