Tiotropium + olodaterol shows clinically meaningful improvements in quality of life
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Keywords
COPD
Quality of life
Long-acting bronchodilator
Tiotropium
Olodaterol
Abbreviations
AE
adverse event
AUC0–3
area under the curve from 0 to 3 h
COPD
chronic obstructive pulmonary disease
FEV1
forced expiratory volume in 1 s
GOLD
Global initiative for chronic Obstructive Lung Disease
FVC
forced vital capacity
LABA
long-acting β2-agonist
LAMA
long-acting muscarinic antagonist
MCID
minimum clinically important difference
SGRQ
St George's Respiratory Questionnaire
TDI
Transition Dyspnoea Index
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Copyright © 2015 The Authors. Published by Elsevier Ltd.