Journal of the American Society of Echocardiography
Clinical InvestigationCongenital Heart DiseaseEvaluation of Ventricular Filling Pressures and Ventricular Function by Doppler Echocardiography in Patients with Functional Single Ventricle: Correlation with Simultaneous Cardiac Catheterization
Section snippets
Patients
In this prospective study, we included all consecutive patients (age < 18 years) with functional single ventricle who underwent simultaneous echocardiography and cardiac catheterization as part of their routine preoperative cardiac evaluation at our institution between 2009 and 2010. Cardiac catheterization for hemodynamic measurements and evaluation of vascular structures was routinely performed before Glenn and Fontan palliation at our center. In all patients, echocardiographic measurements
Results
A total of 32 patients (15 male; mean age, 30.2 ± 22 months) were studied. Characteristics of the study population are shown in Table 1. There were no significant differences in age, gender, and oxygen saturation between the single right ventricle and single left ventricle cohorts (Table 1). The Doppler values obtained are shown in Table 2. Two patients with fused E and A waves and one patient with a significant outflow tract obstruction were excluded from the study. None of the patients in the
Discussion
Echocardiographically obtained pulsed-wave and tissue Doppler has emerged as a very practical tool in the noninvasive estimation of ventricular filling pressures and diastolic function in both adult and pediatric practices.10, 12, 13 In adults with biventricular physiology, an E/E′ ratio < 8 identified patients with normal filling pressures, and a ratio > 15 predicted elevated left ventricular filling pressures (>12 mm Hg).9, 11 Prior studies in pediatric patients with single-ventricle
Conclusions
To the best of our knowledge, this is the first study to simultaneously evaluate the relationship between noninvasive echocardiographically derived Doppler parameters of VEDP and directly measured VEDP in children with functional single ventricle. In functional single ventricles, Doppler echocardiographic parameters correlate modestly with direct measurement of VEDP and may be helpful in identifying patients with elevated filling pressures but not for precise characterization of ventricular
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2019, International Journal of CardiologyCitation Excerpt :In our cohort, the correlation between medial and lateral e′ velocities was only modest. Menon et al. [4] also observed free wall (lateral) e′ velocities to be lower in single ventricle patients with morphologic right ventricles compared to left ventricular morphology. The lack of tissue Doppler data for some of the patients can be explained by our current inability to interpret these findings when acquired.