Original articleSuccessful control of extensive thoracic lymphangiomatosis by irradiation
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Diffuse pulmonary lymphangiomatosis involving lungs and mediastinal soft tissue
2022, American Journal of the Medical SciencesCitation Excerpt :Surgical resection is indicated for localized lung or mediastinal lesions.17 Other treatments include low-fat medium-chain triglyceride diets, interferon-alpha,22 corticosteroids, cyclophosphamide, sirolimus, radiation, somatostatin, propranolol, and bevacizumab.11,12,18-20 We prescribed propranolol for the patient and planned to use bevacizumab if the disease progressed further, both of which have less severe toxicity.
A novel case of lymphangiomatosis in HIV
2017, Experimental and Molecular PathologyCitation Excerpt :Case reports have demonstrated variable success with surgical resection, local radiation, and sclerotherapy, but these approaches are limited to isolated disease only (Bermejo Casero et al., 2004; Satria et al., 2011; Kadakia et al., 2013). Interferon therapy has also been used with marginal success, but again, treatment is limited by significant toxicity and long-term side effects (Kandil et al., 1997; Kadakia et al., 2013). More recently, experimental treatment with systemic VEG-F inhibitors (propranolol, sirolimus, bevacizumab), which inhibit lymphangiogenesis, has been employed in a handful of cases with early reports of success (Ozeki et al., 2011; Reinglas et al., 2011; Aman et al., 2012).
An extrapulmonary manifestation of lymphangioleiomyomatosis: A rare case report
2017, International Journal of Surgery Case ReportsCitation Excerpt :A minimal-fat diet which contains medium-chain fatty acids also provides partial benefits in chylous effusion [3]. In addition, RT can be helpful in intractable cases [5,6]. However, steroids and chemotherapeutics have shown no effect in symptomatic relief.
CO<inf>2</inf> laser resurfacing of intraoral lymphatic malformations: A 10-year experience
2009, International Journal of Pediatric OtorhinolaryngologyCitation Excerpt :Case reports exist of treatment with intralesional steroid injection for tongue lesions [7]. Irradiation has been used for extensive disease [8] especially within the thorax, but is not indicated for cervicofacial lesions secondary to its high morbidity. Sclerotherapy has become an excellent treatment for macrocystic LM, but results have been unimpressive in the treatment of mixed and microcystic disease [2,9].
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