Regular PaperVentilation-perfusion relationships and central haemodynamics in patients with cirrhosis. Effects of a somatostatin analogue
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2004, Revue des Maladies RespiratoiresOctreotide-induced hypoxemia and pulmonary hypertension in premature neonates
2003, Journal of Pediatric SurgeryCitation Excerpt :Torrecillas et al9 showed the vasoconstrictive effect of somatostatin mediated by the somatostatin SRIF receptor-4.10 Octreotide administration elicits a biphasic response wherein there is an initial transiently induced vasoconstriction of the pulmonary arterial vasculature with a subsequent fall to baseline pressure.11 Such a biphasic response may not be present in these 2 premature infants because their vascular smooth muscles have increased vascular resistance while recovering from hyaline membrane disease.12
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