The evolutionary role of secondary metabolites — a review☆
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Functions of secondary metabolites
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2021, iScienceCitation Excerpt :Four of these clusters were missing from the termite-specialist clades, and one BGC was only identified in two of the three termite specialists. BGC lengths are frequently over 10 Kbp (Maplestone et al., 1992), challenging accurate predictions in silico, especially when low N50s cause them to bridge scaffolds. However, we did not identify a significant link between N50 and the number of predicted BGCs (linear model: F1 = 0.004, p = 0.954).
Plant derived coumestrol phytochemical targets human skin carcinoma cells by inducing mitochondrial-mediated apoptosis, cell cycle arrest, inhibition of cell migration and invasion and modulation of m-TOR/PI3K/AKT signalling pathway
2021, Saudi Journal of Biological SciencesCitation Excerpt :In recent years, dietary compounds are involved in one of the chemotherapeutic approaches to tackle cancer with higher efficacy (Alice, 2002). Natural products (polyphenolic compounds in particular) have become an essential part of cancer therapy and prevention as alternative medicine (Foye, 2008; Rachael et al., 1992; Scalbert and Williamson, 2000; Le Marchand, 2002). Phytoestrogens belong to polyphenolic compounds and have been classified into stilbenes (like resveratrol), coumestans (like coumestrol), lignans (like enterodiol) and isoflavones (like genistein).
Recent Applications of Selected Name Reactions in the Total Synthesis of Alkaloids
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Presented at the International Symposium on Biology of Actinomycetes, University of Wisconsin, Madison, WI (USA) 11–16 August 1991.
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Present address: Department of Molecular Biology, Research Institute of Scripps Clinic, 10666 North Torrey Pines Road, La Jolla, CA 92037 (USA) Tel. (619)455-9100.