Journal of Allergy and Clinical Immunology
Intranasal anticholinergic therapy of rhinorrhea
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Effects of 101BHG-D01, a novel M receptor antagonism, on allergic rhinitis in animal models and its mechanism
2023, European Journal of PharmacologyRational use of mucoactive medications to treat pediatric airway disease
2020, Paediatric Respiratory ReviewsThe approach to pediatric cough
2010, Annals of Allergy, Asthma and ImmunologyCitation Excerpt :Although diphenhydramine has been reported to have central antitussive action,42 it should be noted that upper airway cough syndrome due to viral infection is not a histamine-mediated event, and thus antihistamines are ineffective.5 For patients with postnasal drainage refractory to antihistamines (and in allergic rhinitis, intranasal corticosteroids and possibly leukotriene modifiers), intranasal ipratropium bromide provides the drying effect required with minimal adverse effects43 and can be used in children older than 5 years. For patients with chronic upper airway cough syndrome and a history suggestive of allergic rhinitis, skin testing should be performed, and consideration should be given to immunotherapy (if indicated).
The diagnosis and management of rhinitis: An updated practice parameter
2008, Journal of Allergy and Clinical ImmunologyCitation Excerpt :Although cromolyn sodium is less effective than intranasal corticosteroids, it has never been adequately studied to determine its effectiveness in comparison with antihistamines or LT antagonists.435 The nasal anticholinergic ipratropium bromide is effective in reducing rhinorrhea caused by allergic rhinitis, nonallergic rhinitis (including cold-induced rhinitis436 and gustatory rhinitis66), and the common cold.437-447 Ipratropium bromide is only approved (down to the age of 5 years) for the treatment of rhinorrhea, although 1 pediatric study showed modest benefit for controlling nasal congestion.448
Treatment of allergic rhinitis and vasomotor rhinitis. An evidence-based update
2005, FMC Formacion Medica Continuada en Atencion Primaria