Original article
Immediate-type reactions in patients with allergic bronchopulmonary aspergillosis

https://doi.org/10.1016/0091-6749(83)90434-7Get rights and content

Abstract

Allergic features of 38 patients with allergic bronchopulmonary aspergillosis (ABPA) were reviewed. These features included skin reactivity to other inhalant antigens and to molds other than Aspergillus fumigatus (Af) plus clinical manifestations of rhinitis, conjunctivitis, asthma, eczema, urticaria, anaphylaxis, food allergy, and drug allergy. ABPA patients have a high degree of allergic reactivity in all these clinical features, in particular, clearly documented food allergy. These findings differ from those previously reported in ABPA patients in England, where it was noted that patients with ABPA whose asthma began after age 30 had few manifestations of other allergic diseases. By contrast, our patients in the same age group (onset of asthma after age 30) had the same multiple allergic manifestations as younger patients. These results show that ABPA patients are a subset of atopic individuals with a greater predisposition for the development of a wide spectrum of allergic diseases, despite the lack of manifestations of other major immunologic disease patterns.

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Cited by (25)

  • Allergic Bronchopulmonary Aspergillosis

    2012, Clinics in Chest Medicine
    Citation Excerpt :

    Patients with end-stage pulmonary fibrosis may develop pneumothorax,25 clubbing, cyanosis, and dependence on supplemental oxygen.26 When compared with adult-onset asthmatics, patients with ABPA have a higher incidence of other allergic conditions, such as allergic rhinitis, atopic dermatitis, food allergy, and drug allergy.27 The diagnosis of ABPA should be suspected in an asthmatic with peripheral eosinophilia, elevated IgE, immediate cutaneous reactivity to Af, recurrent infiltrates, and central bronchiectasis (CB).

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    1998, Immunology and Allergy Clinics of North America
  • Epidemiology of allergic bronchopulmonary aspergillosis

    1998, Immunology and Allergy Clinics of North America
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Supported by U.S.P.H.S. Grant AI 11403 and the Ernest S. Bazley Grant.

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