Original contributionPulmonary vascular involvement in sarcoidosis: A report of 40 autopsy cases☆
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2018, The Lancet Respiratory MedicineCitation Excerpt :Typically, giant cells contain intracytoplasmic inclusions, such as Schaumann bodies, asteroid bodies, and blue bodies of calcium oxalates. Granulomas can invade the airway and vascular compartment, as seen in surgical specimens (figure 2B), whereas the uninvolved lung parenchyma has a normal appearance.46 In chronic disease, as chronic lymphocytic infiltrate vanishes, granulomas tend to become increasingly fibrotic and enlarge to form hyalinised nodules rich with densely eosinophilic collagen (figures 2C and 2D).
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Supported in part by a grant from the Intractable Diseases Research Committee and the Interstitial Pulmonary Disease Research Committee, Ministry of Health and Welfare of Japan.
Copyright © 1992 Published by Elsevier Inc.