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Spirometric and radiological evaluation of the remnant lung long after major pulmonary resection: can compensatory phenomena be recognized in clinical cases?

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Abstract

Purposes

The purpose of this study was to investigate the compensatory phenomena after lung resection in clinical cases by evaluating the spirometric and radiological parameters.

Methods

Forty patients undergoing lobectomy for stage IA lung cancer were divided into the following groups: (A) patients with <10 (n = 20) and (B) patients with ≥10 resected subsegments (n = 20). Comparisons were made of the predicted and observed postoperative values of spirometry and radiological parameters, such as lung volumetry and the “estimated lung weight”. Predicted values were based on the number of resected subsegments. The postoperative time to re-evaluation was at least 1 year for both groups.

Results

The predicted postoperative values of spirometry underestimated the actual values, and the differences were more significant in group B (forced vital capacity, p = 0.006, forced expiratory volume in 1 s, p = 0.011). Focusing on the remnant lungs on the surgical side, group B had significantly larger % postoperative lung volumes (161 ± 6.0 %) and % estimated lung weight (124 ± 5.4 %) than did group A (114 ± 3.8 %, p < 0.0001; 89.5 ± 4.4 %, p < 0.0001, respectively).

Conclusions

Major lung resection in clinical cases causes a compensatory restoration of the pulmonary function and tissue.

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Acknowledgments

This study was supported by Grants-in-Aid for Scientific Research (C) 23592054 (to T.M.) from the Japan Society for the Promotion of Science (JSPS KAKENHI Grant Number 23592054).

Conflict of interest

Teruaki Mizobuchi and the co-authors have no conflicts of interest to declare.

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Authors and Affiliations

  1. Department of General Thoracic Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ward, Chiba, Chiba, Japan

    Teruaki Mizobuchi, Hironobu Wada, Yuichi Sakairi, Hidemi Suzuki, Takahiro Nakajima, Tetsuzo Tagawa, Takekazu Iwata, Shigetoshi Yoshida & Ichiro Yoshino

  2. Department of Radiology, Graduate School of Medicine, Chiba University, Chiba, Japan

    Ken Motoori

Authors
  1. Teruaki Mizobuchi
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  2. Hironobu Wada
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  3. Yuichi Sakairi
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  4. Hidemi Suzuki
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  5. Takahiro Nakajima
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  6. Tetsuzo Tagawa
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  7. Takekazu Iwata
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  8. Ken Motoori
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  9. Shigetoshi Yoshida
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  10. Ichiro Yoshino
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Corresponding author

Correspondence to Teruaki Mizobuchi.

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Mizobuchi, T., Wada, H., Sakairi, Y. et al. Spirometric and radiological evaluation of the remnant lung long after major pulmonary resection: can compensatory phenomena be recognized in clinical cases?. Surg Today 44, 1735–1743 (2014). https://doi.org/10.1007/s00595-013-0702-6

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  • DOI: https://doi.org/10.1007/s00595-013-0702-6

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