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Imaging of macrophage-related lung diseases

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Abstract

Macrophage-related pulmonary diseases are a heterogeneous group of disorders characterized by macrophage accumulation, activation or dysfunction. These conditions include smoking-related interstitial lung diseases, metabolic disorders such as Niemann–Pick or Gaucher disease, and rare primary lung tumors. High-resolution computed tomography abnormalities include pulmonary ground-glass opacification secondary to infiltration by macrophages, centrilobular nodules or interlobular septal thickening reflecting peribronchiolar or septal macrophage accumulation, respectively, emphysema caused by macrophage dysfunction, and honeycombing following macrophage-related lung matrix remodeling.

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  1. Department of Radiology, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK

    Katharina Marten & David M. Hansell

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Marten, K., Hansell, D.M. Imaging of macrophage-related lung diseases. Eur Radiol 15, 727–741 (2005). https://doi.org/10.1007/s00330-004-2554-3

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