Morning (breakfast) | Afternoon (lunch) | Evening (dinner) | Total pills per day | |
2-week titration schedule according to prescribing information [8] | ||||
Days 1–7 | 1 | 1 | 1 | 3 |
Days 8–14 | 2 | 2 | 2 | 6 |
Days ≥15 | 3 | 3 | 3 | 9 |
Modified 4-week titration schedule [26] | ||||
Days 1–14 | 1 | 1 | 1 | 3 |
Days 15–28 | 2 | 2 | 2 | 6 |
Days ≥29 | 3 | 3 | 3 | 9 |
Each pill is 267 mg. Full dose of pirfenidone is 2403 mg·day−1.