| Inflammation type |
| Implication of neutrophils |
| Signalling pathways |
| Excessive activation of transcription factors: nuclear factor-κB and activator protein-1 |
| Increase in mitogen-activated protein kinase activity |
| Cooperation |
| Impairment of β2-adrenoreceptor function |
| Imbalance in corticosteroid receptors (decreased α/β ratio) |
| Raised histone acetylation |
| Reduced histone-deacetylase expression |
| Inflammation and oxidative stress consequences |