First author [ref.] | Main conclusion | SIGN grade | Study type | Exposure/ occupation | Subjects n |
Anees [31] | No relationship | 2+ | Longitudinal | Various HMW and LMW agents | 156 |
Malo [20] | + (Female sex favours good prognosis) | 2+ | Longitudinal | Various HMW and LMW agents | 80 |
Park [21] | No relationship | 2- | Longitudinal | TDI | 41 |
Gassert [39] | + (Male sex favours good prognosis) | 2- | Longitudinal | Various | 55 |
SIGN: Scottish Intercollegiate Guidelines Network; HMW: high molecular weight; LMW: low molecular weight; TDI: toluene diisocyanate. +: effect of sex on asthma outcome.