First author [ref.] | Main conclusion | SIGN grade | Study type | Exposure/occupation | Subjects n |
Merget [10] | + | 2- | Cohort study | Platinum salts | 275 |
Descatha [28] | No relationship | 2+ | Case series | Various HMW and LMW agents | 227 |
Chang-Yeung [32] | + | 2- | Longitudinal | Western red cedar | 38 |
Cote [12] | No relationship | 2+ | Longitudinal | Plicatic acid (Western red cedar) | 48 |
Valentino [29] | No relationship | 2+ | Longitudinal | TDI | 50 |
Sorgdrager [13] | + | 2- | Longitudinal | Fluorides | 122 |
Park [16] | No relationship | 2- | Longitudinal | TDI | 35 |
Lozewicz [18] | No relationship | 2+ | Longitudinal | Isocyanates (TDI, MDI) | 56 |
Anees [31] | No relationship | 2+ | Longitudinal | Various HMW and LMW agents | 156 |
Malo [20] | No relationship | 2+ | Longitudinal | Various HMW and LMW agents | 80 |
Mapp [22] | No relationship | 2- | Longitudinal | TDI | 35 |
Gassert [39] | No relationship | 2- | Longitudinal | Various | 55 |
Labreque [23] | No relationship | 2- | Longitudinal | Isocyanates | 79 |
Soyseth [24] | No relationship | 2+ | Longitudinal | Fluorides | 38 |
Merget [38] | + | 2- | Longitudinal | Platinum salts | 24 |
SIGN: Scottish Intercollegiate Guidelines Network; HMW: high molecular weight; LMW: low molecular weight; TDI: toluene diisocyanate; MDI: methylene diphenyl diisocyanate. +: relationship between smoking at diagnosis and worse asthma outcome.