Table 3
Natural course of pre-invasive central airway lesions
Pre-invasive lesion
Regression %
Persistence %
Progression to CIS/invasive carcinoma %
Metaplasia
37–42
29
0–9
Mild/moderate dysplasia
64
22
0–11
Severe dysplasia
52–63
16
11–56
CIS
12
70
21–67
CIS: carcinoma
in situ
.