Inadequate clinical response for patients who were initially in WHO FC II or III: |
1) Resulting clinical status defined as stable and not satisfactory |
2) Resulting clinical status defined as unstable and deteriorating |
Inadequate clinical response for patients who were initially in WHO FC IV: |
1) No rapid improvement to WHO FC III or better |
2) Resulting clinical status defined as stable and not satisfactory |
WHO FC: World Health Organization functional class. Reproduced from 1 with permission from the publisher.