First evaluation | After 18 months of evolution without PEA | 6 months after PEA | ||
At rest | Exercise (100 W) | |||
WHO functional class | II | III | I | |
6MWD m | 540 | 477 | 748 | |
Pra mmHg | 2 | NA | 6 | 4 |
P̄pa mmHg | 31 | 69 | 43 | 18 |
Ppcw mmHg | 2 | NA | 4 | 6 |
CO L·min−1 | 4.6 | 12.3 | 4.7 | 5.8 |
TPR dyn·s·cm−5 | 539 | 449 | 732 | 248 |
SV,O2 % | 68 | 27 | 63 | 73 |
Decision for therapy | VKA | VKA | VKA | |
Patient declined PEA | Patient accepted PEA |
PEA: pulmonary thromboendarterectomy; WHO: World Health Organization; 6MWD: 6-min walk distance; Pra: right atrial pressure; P̄pa: mean pulmonary arterial pressure; Ppcw: pulmonary capillary wedge pressure; CO: cardiac output; TPR: total pulmonary resistance; SV,O2: mixed venous oxygen saturation; VKA: oral vitamin K antagonist anticoagulation.