Structural and functional differences of ELR-negative CXC chemokines in the regulation of vascular remodelling
| Chemokine | Effect on angiogenesis | Relevant structural motif | Receptor through which effects on angiogenesis are mediated |
| CXCL4 | Angiostatic | D-G-D-L-Q-C-L-C | CXCR3 |
| CXCL9 | Angiostatic | V-R-K-G-R-C-S-C | CXCR3 |
| CXCL10 | Angiostatic | S-R-T-V-R-C-T-C | CXCR3 |
| CXCL11 | Angiostatic | F-K-R-G-R-C-L-C | CXCR3 |
ELR motif: a conserved amino acid sequence of Glu-Leu-Arg in the amino terminus of CXC chemokines. Reproduced from [11] with permission from the publisher.