Table 1—

Adequate therapy forβ-lactamase-producing pathogens

AntibioticESBLAmpC
Third-generation cephalosporins
Cefepime+++
Fluoroquinolones+/–+
Piperacillin/tazobactam+/–+/–
Tigecycline++++
Carbapenem++++++
  • ESBL: extended-spectrum β-lactamases; AmpC: Ampicillin resistance gene C. –: not effective; +: effective; ++: more effective; +++: most effective; +/–: effective against some, but not all, β-lactamases.