RT Journal Article SR Electronic T1 Personalised medicine in interstitial lung diseases JF European Respiratory Review JO EUROPEAN RESPIRATORY REVIEW FD European Respiratory Society SP 170117 DO 10.1183/16000617.0117-2017 VO 27 IS 148 A1 Maria A. Kokosi A1 George A. Margaritopoulos A1 Athol U. Wells YR 2018 UL http://err.ersjournals.com/content/27/148/170117.abstract AB Interstitial lung diseases in general, and idiopathic pulmonary fibrosis in particular, are complex disorders with multiple pathogenetic pathways, various disease behaviour profiles and different responses to treatment, all facets that make personalised medicine a highly attractive concept. Personalised medicine is aimed at describing distinct disease subsets taking into account individual lifestyle, environmental exposures, genetic profiles and molecular pathways. The cornerstone of personalised medicine is the identification of biomarkers that can be used to inform diagnosis, prognosis and treatment stratification. At present, no data exist validating a personalised approach in individual diseases. However, the importance of the goal amply justifies the characterisation of genotype and pathway signatures with a view to refining prognostic evaluation and trial design, with the ultimate aim of selecting treatments according to profiles in individual patients.Personalised medicine provides a potential road map for guiding clinical care in interstitial lung diseases http://ow.ly/xZop30iQOoQ