PT - JOURNAL ARTICLE AU - Ioannis Psallidas AU - Ioannis Kalomenidis AU - Jose M. Porcel AU - Bruce W. Robinson AU - Georgios T. Stathopoulos TI - Malignant pleural effusion: from bench to bedside AID - 10.1183/16000617.0019-2016 DP - 2016 Jun 01 TA - European Respiratory Review PG - 189--198 VI - 25 IP - 140 4099 - http://err.ersjournals.com/content/25/140/189.short 4100 - http://err.ersjournals.com/content/25/140/189.full SO - EUROPEAN RESPIRATORY REVIEW2016 Jun 01; 25 AB - Malignant pleural effusion (MPE) is a common but serious condition that is related with poor quality of life, morbidity and mortality. Its incidence and associated healthcare costs are rising and its management remains palliative, with median survival ranging from 3 to 12 months. During the last decade there has been significant progress in unravelling the pathophysiology of MPE, as well as its diagnostics, imaging, and management. Nowadays, formerly bed-ridden patients are genotyped, phenotyped, and treated on an ambulatory basis. This article attempts to provide a comprehensive overview of current advances in MPE from bench to bedside. In addition, it highlights unanswered questions in current clinical practice and suggests future directions for basic and clinical research in the field.This review provides up to date knowledge for malignant pleural effusion covering aspects from bench to bedside http://ow.ly/10w7vN