PT - JOURNAL ARTICLE AU - Florence Jeny AU - Diane Bouvry AU - Olivia Freynet AU - Michael Soussan AU - Michel Brauner AU - Carole Planes AU - Hilario Nunes AU - Dominique Valeyre TI - Management of sarcoidosis in clinical practice AID - 10.1183/16000617.0013-2016 DP - 2016 Jun 01 TA - European Respiratory Review PG - 141--150 VI - 25 IP - 140 4099 - http://err.ersjournals.com/content/25/140/141.short 4100 - http://err.ersjournals.com/content/25/140/141.full SO - EUROPEAN RESPIRATORY REVIEW2016 Jun 01; 25 AB - Sarcoidosis is a systemic disease of unknown cause with very diverse presentation, outcome, severity and need for treatments. While some presentations may be very typical, for many patients, the presentation is nonspecific, with shared associations with other diseases at times being by far more frequent or misleading, which can be a cause of significant delay and often several consultations before a diagnosis of sarcoidosis can be confirmed. This is particularly the case when pulmonary manifestations are in the forefront. The diagnosis relies on three well-known criteria. In clinical practice, these criteria are not easily implemented, particularly by physicians without expertise in sarcoidosis, which can lead to a risk of either under- or over-diagnosis. Qualifying the presentation according to sarcoidosis diagnosis is essential. However, it is often not easy to classify the presentation as typical versus compatible or compatible versus inconsistent. Further investigations are needed before any other hypothesis is to be considered. It is important to detect events and to determine whether or not they are indicative of a flare of sarcoidosis. Eventually, treatment needs to be related to the correct indications. The evaluation of the efficacy and safety of treatments is crucial. To address such issues, we present five emblematic cases that illustrate this.Showing emblematic cases is the best way to illustrate the multiple conditions to deal with for managing sarcoidosis http://ow.ly/10A5Yv