RT Journal Article SR Electronic T1 An official American Thoracic Society/European Respiratory Society statement: research questions in COPD JF European Respiratory Review JO EUROPEAN RESPIRATORY REVIEW FD European Respiratory Society SP 159 OP 172 DO 10.1183/16000617.00000315 VO 24 IS 136 A1 Bartolome R. Celli A1 Marc Decramer A1 Jadwiga A. Wedzicha A1 Kevin C. Wilson A1 Alvar A. Agustí A1 Gerard J. Criner A1 William MacNee A1 Barry J. Make A1 Stephen I. Rennard A1 Robert A. Stockley A1 Claus Vogelmeier A1 Antonio Anzueto A1 David H. Au A1 Peter J. Barnes A1 Pierre-Regis Burgel A1 Peter M. Calverley A1 Ciro Casanova A1 Enrico M. Clini A1 Christopher B. Cooper A1 Harvey O. Coxson A1 Daniel J. Dusser A1 Leonardo M. Fabbri A1 Bonnie Fahy A1 Gary T. Ferguson A1 Andrew Fisher A1 Monica J. Fletcher A1 Maurice Hayot A1 John R. Hurst A1 Paul W. Jones A1 Donald A. Mahler A1 François Maltais A1 David M. Mannino A1 Fernando J. Martinez A1 Marc Miravitlles A1 Paula M. Meek A1 Alberto Papi A1 Klaus F. Rabe A1 Nicolas Roche A1 Frank C. Sciurba A1 Sanjay Sethi A1 Nikos Siafakas A1 Don D. Sin A1 Joan B. Soriano A1 James K. Stoller A1 Donald P. Tashkin A1 Thierry Troosters A1 Geert M. Verleden A1 Johny Verschakelen A1 Jorgen Vestbo A1 John W. Walsh A1 George R. Washko A1 Robert A. Wise A1 Emiel F.M. Wouters A1 Richard L. ZuWallack YR 2015 UL http://err.ersjournals.com/content/24/136/159.abstract AB Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality and resource use worldwide. The goal of this official American Thoracic Society (ATS)/European Respiratory Society (ERS) Research Statement is to describe evidence related to diagnosis, assessment, and management; identify gaps in knowledge; and make recommendations for future research. It is not intended to provide clinical practice recommendations on COPD diagnosis and management. Clinicians, researchers and patient advocates with expertise in COPD were invited to participate. A literature search of Medline was performed, and studies deemed relevant were selected. The search was not a systematic review of the evidence. Existing evidence was appraised and summarised, and then salient knowledge gaps were identified. Recommendations for research that addresses important gaps in the evidence in all areas of COPD were formulated via discussion and consensus. Great strides have been made in the diagnosis, assessment and management of COPD, as well as understanding its pathogenesis. Despite this, many important questions remain unanswered. This ATS/ERS research statement highlights the types of research that leading clinicians, researchers and patient advocates believe will have the greatest impact on patient-centred outcomes. ATS/ERS statement highlighting research areas that will have the greatest impact on patient-centred outcomes in COPD http://ow.ly/LXW2J