PT - JOURNAL ARTICLE AU - M.R. Mehta AU - D.W. Connell AU - M.I. Wickremasinghe AU - O.M. Kon TI - The use of thoracic computed tomography scanning and EBUS-TBNA to diagnose tuberculosis of the central nervous system: two case reports AID - 10.1183/09059180.00002910 DP - 2010 Dec 01 TA - European Respiratory Review PG - 345--347 VI - 19 IP - 118 4099 - http://err.ersjournals.com/content/19/118/345.short 4100 - http://err.ersjournals.com/content/19/118/345.full SO - EUROPEAN RESPIRATORY REVIEW2010 Dec 01; 19 AB - Herein, we report two cases of tuberculosis (TB) of the central nervous system where accessing the cerebrospinal fluid for diagnostic purposes was relatively or absolutely contraindicated at presentation. The finding of mediastinal lymphadenopathy on thoracic computed tomography scans, which was not visible on plain chest radiography, allowed endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) of these lymph nodes to support the diagnosis of TB in each patient and rule out other disease processes. EBUS-TBNA is a new bronchoscopic technique and in this case report appears to be a safe and useful option in the diagnosis of TB. Moreover, it proved to be so in cases where the main focus of disease was outside the thorax.